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Based on this limited information we conclude the following points: Glutathione has positive effects on lighting the skin tone The effects of Glutathione as a skin-whitening agent havent been well established Glutathione capsules & creams may be effective (& reasonably safe) in skin-whiteninig, but long-term effects are still uncertain & unknown For Glutathione injections, we do not have sufficient safety information

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However, when berberine is long-term administered to 6-OHDA-induced rat model of Parkinsons disease, monitoring for adverse symptoms is required

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Most brands under-dose vitamin C, making glutathione less effective