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Venography assessment includes rats having a full presentation of collaterals (i.e., presentation of pterigopalatinal veins and nasal veins and presentation of the ophthalmic vein, angularis vein, facial anterior and posterior vein, and facial vein, or through cerebri superior veins, sinus cavernosus, sinus petrosus superior and inferior, sinus transversus, through jugular external vein, subclavia vein through superior caval veins after venography into the superior sagittal sinus

Higher absorption for large doses : For large oral doses of supplemental vitamin B12 (25010,000 mcg), approximately 0.9 to 1.2% is absorbed through passive diffusion, which does not require intrinsic factor