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In AML, overexpression of EZH2 results in the downregulation of tumor suppressor genes, such as p16INK4a and p53 , which promotes leukemia cell proliferation and increases resistance to chemotherapy (Tsai et al., 2022)

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Effects on Proinflammatory Enzymes Various inflammatory mediators including prostaglandins (PGs) i.e., PGE2, 6-keto prostaglandin F1 (6-keto-PGF1) and other active lipids are found in all human cells