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Tails were solubilized in 300 L solubilization buffer (10X SET, 100 mM NaCl, 100 g/mL Proteinase K (Bio Basic PB0451-250)) at 55 C overnight

Metagenome-wide association of microbial determinants of host phenotype in Drosophila melanogaster

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This review integrates mechanistic insights with translational advances, outlining how dysregulation of chaperones, autophagy-mitophagy, the ubiquitinproteasome system, and ER stress pathways drive human diseases, while highlighting emerging therapeutic platforms, from pharmacological chaperones and autophagy modulators to targeted protein degradation technologies, CRISPR screens, spatial biology, and AI-guided drug discovery

Peptide therapy addresses follicle repair, inflammation, microcirculation, and systemic regenerative capacity