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doi: 10.1016/j.bbrc.2007.03.025 95 BoetsEDerooverLHoubenEVermeulenKGomandSVDelcourJAet al

The BAC-concentrating effect is most meaningful during more significant fluid loss from heat, altitude, intense exercise, or illness not from skipping one glass of water

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In such a way, defined direct effect may better serve the ischemia purpose than complex procedures with L-NAME