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The original paper is in Mandarin and you can access it here (paywall): #Type2Diabetes #DiabetesResearch #Obesity #GLP1 #Semaglutide #Dorzagliatin #MetabolicHealth #HuaMedicine To view or add a comment, sign in A newly published peer-reviewed scientific paper from China adds to the growing body of evidence around the benefits that dorzagliatin (GKA) in combination with the popular semaglutide (GLP-1RA) delivers superior glycemic control, weight reduction, and islet cell function improvement when compared with semaglutide monotherapy in obese patients with Type 2 diabetes mellitus (T2DM), with a comparable safety profile

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An important antioxidant, l-glutathione, is produced within the cells

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Pharmacological therapies Pharmacological compounds, acting through inhibition of NF-B (corticosteroidsglucocorticoids), downregulation of histone deacetylase activity (HDAC inhibitors), modulation of the utrophin level, or angiotensin activity (angiotensin-converting enzyme inhibitors