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Citalopram, a selective serotonin reuptake inhibitor that enhances serotonergic neurotransmission by blocking serotonin reuptake at the presynapse, restored motor coordination, aggregation, and neuronal survival in mice, and aripiprazole, an antipsychotic whose efficacy mainly reflects a combined action on dopaminergic and serotonergic signaling, reduced abundance, aggregation, and toxicity of mutant ATXN3 in vivo

NPs were collected and purified by centrifugation (10,733 g 40 min)

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Umbricht D, Yoo K et al (2010)

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