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3537 It has been proposed that metformin and phenformin inhibit thiamine absorption through inhibition of the human thiamine transporter (THTR2) in the small intestine, 38 a finding recently confirmed to be clinically relevant, 39 particularly in at-risk populations

(6) When the clinical situation allows, repeating the test after the patient has stabilized shows whether the abnormality was passing or persistent

Theoretical concerns include off-target cell death, immune burden from clearing many cells at once, impaired wound healing, and injection-site irritation

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