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Perspectives such as this one, in addition to focused standalone articles, will help drug design programs appreciate that simply adding fluorine as a replacement for hydrogen by virtue of its small atomic size, greater electronegativity and greater bond dissociation energy (Gillis et al

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High Nrf2 expression increases the catalytic subunit activity of glutamate-cysteine ligase (GCLC)

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In 1961, Leonard Hayflick demonstrated that human fetal cells have 50 to 60 generations of limited replication potential, which was subsequently termed the Hayflick limit or replicative senescence