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Mertelsmann R, Grossbard E, Incefy G, Beck JD, Andreeff M , Koziner B, Clarkson B, Moore MAS

showed that nightly GHRH injections in healthy older men increased GH secretion and improved body composition parameters over a six-month period (4)

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(71) provided a comprehensive overview of various colon-targeted delivery systems, including resistant starch and natural biopolymers, emphasizing their shared mechanism of action: bypassing enzymatic degradation in the upper gastrointestinal tract and undergoing microbial enzyme-triggered breakdown in the colon to release bioactive compounds