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FIGURE 1 2.1 Lipid metabolism and ferroptosis induction in melanoma Ferroptosis is closely linked to dysregulated lipid metabolism in melanoma, in which polyunsaturated fatty acid (PUFA) metabolism serves as the central molecular mechanism

Moreover, GA combined with low-level laser irradiation increased ROS production and decreased GPX4 activity to trigger ferroptosis and apoptosis of breast and melanoma cancer cells ( Honokiol (HNK) is a biphenolic metabolite in Magnolia officinalis Rehder and E.H.Wilson [Magnoliaceae

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Kobayashi N, Hattori Y, Nagata T et al (2018) Noise peak filtering in multi-dimensional NMR spectra using convolutional neural networks