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Extensive plaques all around the tunica albuginea can make the penis shaft look indented in the middle, like an hourglass i.e., an hourglass deformity

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BBB dysfunction is considered a key mechanism through which peripheral inflammation contributes to CNS pathology in ASD, allowing inflammatory molecules and immune cells to infiltrate neural tissue and exacerbate neuroinflammation (Sochocka et al., 2019)

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Mitochondria are unique organelles, coordinating metabolic and apoptotic crosstalk to tightly regulate cell survival 10