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ER+ breast cancer cells were incubated with retrovirus or lentiviral supernatants in the presence of 8 g/mL of polybrene (Sigma) for 16 h

Zhao S, Calvert L, Chang S, Arlinghaus RB, Guo JQ, Siciliano M, Riley R, Kantarjian H, Andreeff M

Glycine This amino acid makes up about a third of collagen and also acts as a neurotransmitter

A single molecule that activates both pathways simultaneously

This functional RBC storage lesion correlated with significant defects in glutathione (a central molecular player in cellular redox capacity), increased purine oxidation, and increased glycolysis (an expected shift in G6PD deficiency)