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Consequently, inhibiting glycolysis with 2-deoxy-d-glucose (2-DG), which is a glucose analog that competitively binds to hexokinase, postpones the malignant progression of endometrial cancer mediated by histone lactylation by suppressing cell proliferation and migration and inducing apoptosis

BMJ 315, 629634

-Ketoglutarate may contribute to the restoration of ovarian reserve and improve pregnancy rates in a CTX-induced POI rat model, potentially by inhibiting Caspase-3 activity (Talebi et al., 2020

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, the 10-year disease-specific survival rate and 10-year recurrence-free survival (RFS) rate in 111 cases of M0 minimally invasive type (capsular invasion only) were excellent, at 100% and 98% or more, respectively [146]