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3A illustrates a core subset of these differentially expressed genes (DEGs) based on stringent overlap criteria, only a small group of genes ( n = 25) overlapped concordantly (i.e., up- or downregulated in both strains), highlighting the distinct regulatory adjustments driven by glutathione depletion

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A promising strategy involves engineering sequentially responsive nanoplatforms capable of recruiting immune cells before triggering the controlled release of metabolic modulators, thereby aligning drug action with immunological processes

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