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Interestingly, in severe cases, many vital tissues, including those with little ACE2 expressed are severely damaged by COVID-19 infection [45]

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Astrocytes, through their various functions, are crucial to develop and maintain a healthy CNS and they are key players in many acute and chronic CNS diseases (Liu and Chopp, 2016

Moreover, RSVmediated activation and expression of SIRT1 reduce alphasynuclein aggregation in PD (Donmez et al., 2012)