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Our experiments reveal that zero-valent CuPd NPs outperform divalent copper nanoparticles (Ox-CuPd NPs) by displaying superior catalytic performance and sustaining ROS generation through a dual approach integrating peroxidase-like (POD-like) activity and Cu + release

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When UVB-induced CPDs and 6-4PPs are incorrectly resolved or UVA-induced oxidation lesions are not repaired timely, mutations including C: G T: A transition, CC:GG TT: AA tandem mutations or A: T T: A transversion will form [78,79,80]

More recent multicenter data ( n = 42, 2025) confirm doseresponse benefits and highlight early treatment ( C (p.Met340Thr) showed that riboflavin deficiency further reduced AIFM1 protein, while high-dose riboflavin partially reversed this loss and improved respiratory chain activity (53)

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