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Description

Integrating mapping-, assembly-and haplotype-based approaches for calling variants in clinical sequencing applications

Neoplasma 27 , 101106 (1980)

In glaucomatous lamina cribrosa cells, increased levels of unmethylated DNA in the TGF1 promoter were observed, along with increased expression of TGF 1, TGF2 , COL1A1 , and -SMA (McDonnell et al., 2016), ultimately promoting fibrosis (Figure 5E)