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Debido que la enzima oxoprolinasa est ampliamente distribuida en los tejidos, la medida indirecta de su actividad permite inferir un ndice de la actividad de sntesis de GSH y de su homeostasis empleando como sustrato 13 C-oxotiazolidina y cuantificando la presencia de 13 CO 2 en el aire espirado, Consecuentemente, el test de 13 C-oxotiazolidina permite la implementacin y el seguimiento de terapias, adems de caracterizar a los individuos segn su tasa metablica basal para oxotiazolidina y su capacidad de respuesta a una injuria controlada (47)

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Future work will be required to determine the timing of these two key phosphorylations within LIR and PRTxR and the identity of the kinases that impart them on Axin to promote its multi-pronged interaction with GSK

The extract works by helping to bind amino acids, which are necessary for the formation of collagen and elastin

Bioinformatics 26, 24602461