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The neurovascular unit is usually considered to represent the integrated contributions of endothelial cells, mural cells (pericytes and smooth muscle cells (SMCs)), astrocyte endfeet and other cells, along with basement membranes (BMs), to bloodbrain barrier (BBB) function

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Glutathione is a tripeptide made up of three essential amino acids, including cysteine, glycine, and glutamic acid

The model-derived AUCR for both probe drugs was within ~10% of the observed AUCR