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People with copper-related disorders or known sensitivities, and those who are pregnant or breastfeeding, are typically not candidates

Am J Obstet Gynecol 187:225226 Boxer AL, Kramer JH, Johnston K, Goldman J, Finley R, Miller BL (2005) Executive dysfunction in hyperhomocystinemia responds to homocysteine-lowering treatment

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So that there's not any question as to who should use the device and who should not, or where the device should use and where it should not be used