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Choline, inositol, and methionine are studied for their roles in hepatic phosphatidylcholine production (required for VLDL export of fat from the liver), methylation cycle function, and one-carbon metabolism pathways central to NAFLD and metabolic syndrome research

Cycloalkynyl groups can also contain one or more double carbon-carbon bonds, including, for example and not restricted to, the cyclooct-4-en-2-ynyl group and similar

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We break down further details of these flexibility and convenience options in the following section