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This procedure has shown excellent results in reducing pain and improving function, especially when other treatments have failed

However, further clinical validation is still required (Ye et al., 2024)

Andreasson, U

Indeed, genes reported to be regulated by known PXR ligands are CYP1A1, CYP2C8, CYP2C9, MDR1, MRP2, and members of the UGT, sulfotransferase, and carboxylesterase families (Goodwin, Redinbo, and Kliewer, 2002)