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In general, the transporter-mediated passage of compounds across the cellular membrane can be investigated using several methods including in vivo cerebral microdialysis technique, in situ brain perfusion technique and PET imaging in transporter-knockout animals or using selective transporter inhibitors and substrates (112, 118, 196,197,198)

This balance of efficacy and tolerance represents the optimization goal

Conversely, L-carnitine transports long-chain fatty acids into mitochondria, where these fatty acids are oxidized to produce energy

J Biol Chem 286 , 4161641625 (2011)

This not only provides an important theoretical basis but also offers a concentration reference for the rational application of quercetin in the phytoremediation of Cd contaminated soils