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When artemisinin consumes heme 25,26 (or iron 27 ) and produces free radicals or heme-artemisinin adducts to inhibit heme crystallization 28 , even accelerating the breakdown of hemozoin 5 , it simultaneously inevitably interferes the normal formation and degradation of hemozoin, uses up iron by forming iron-artemisinin within the parasites, interferes or interrupts the transport and utilization of iron, thereby finally leading to death of the malaria parasites

They function as targeted biological messengers, instructing your body to turn on specific healing cascades, downregulate systemic inflammation, and accelerate tissue repair

& Daaka, Y

doi: 10.4238/gmr.15027558

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