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Following incubation, cells were rinsed in PBS then incubated with WST-1 reagent (diluted 1:10 into fresh starved media (Roche, UK)) and incubated at 37 C for 4 h in a cell culture incubator according to manufacturers instructions

Researchers found that skin treated with the 2% KYOWA oxidized glutathione location had significant whitening over the placebo group, said Ryusuke Nakagiri, Senior Director of Strategic Science at Kyowa Hakko USA

Journal of Materials Chemistry B

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Because these acids remove dead skin cells and debris, they also help to ensure that all skincare applied afterward works more effectively and penetrates deeper into the skin