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Both mitochondrial biogenesis and mitophagy increased with exercise, giving hepatocytes resilience to different stressors induced by NAFLD with increases in PGC1alpha, Tfam, Mfn1 and Mfn2 (Ghareghani et al., 2018[41]

Reville PK, MD, MPH, Kantarjian H, MD, Borthakur G, MD, Pemmaraju N, MD, DiNardo CD, MD, MSCE, Sasaki K, MD, PhD, Daver N, MD, Issa GC, MD, Ohanian M, DO, Montalban-Bravo G, MD, Short NJ, MD, Jain N, MD, Bhalla KN, MD, Jabbour EJ, MD, Ferrajoli A, MD, Takahashi K, MD, PhD, Rausch CR, PharmD, Malla R, RN, BSN, Marek K, Brandt M, BS, Popat UR, MD, Andreeff M , MD, PhD, Garcia-Manero G, MD, Konopleva M, MD, PhD, Ravandi F, MBBS, Kadia TM, MD