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Perhaps most important, given that CVD accrues as a function of advancing age, is evidence from rodent models that exercise induced cardioprotection is effective against ischemic insults in both young and old animals (Starnes et al., 2003

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Statements Author contributions MoA: Investigation, Validation, Visualization, Writing original draft, Writing review and editing

Results from the application may be more localized and gradual compared to supplementation