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Environmental Stressors Smoking, excessive alcohol consumption, and chronic sleep deprivation are the "big three" for depleting glutathione

As a result of its duty in nerve health as well as neurotransmitter signaling, vitamin B12 benefits cognitive function and also is used to decrease the threat of neurodegenerative conditions, including Alzheimers condition and dementia

doi: 10.1530/JME170068 206 GiustinaAWehrenbergWB

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In addition, a case-control study ( n = 257 cases, 133 controls) in 1993 reported that lower riboflavin intake, assessed via 24 h dietary recall, was associated with increased risk of cervical intraepithelial dysplasia, an early stage proceeding invasive cervical cancer 139