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The inhibition of Topo II leads to a loss of chromosomal supercoiling and furthermore results in the upregulation of oxidative phosphorylation (Nosal et al., 2014)

Striatal glutamate and the conversion to psychosis: a prospective 1H-MRS imaging study

339 The other therapies with specific advantages were found to be superior to the common strategies in treating elderly patients but limited to some specific types of cancer