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a single poor reconstitution or unnecessary freeze-thaw cycle represents a proportionally larger loss of research material

The chart separates that laboratory snapshot from the effect of sustained dosing

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Patients should be advised to: Aim for 6-8 glasses of fluid daily (approximately 1.52 litres), as recommended by the NHS, unless on a fluid restriction Note: patients with heart failure, chronic kidney disease, or other conditions requiring fluid restriction should follow their clinician's specific guidance Increase fluid consumption during episodes of nausea, vomiting, or diarrhoea Monitor urine colour as a simple indicator of hydration status (pale yellow suggests adequate hydration) Ensuring adequate electrolyte intake through dietary sources is essential

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