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In MR, genetic variants are applied as instrumental variables (IVs) to access the potential causal relationship between exposure and outcome due to the random distribution of these variants during meiosis ( Materials and methods Study design An overview of the bidirectional and unidirectional two-sample MR designs is presented in Figure 2

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Cancer growth can result from unregulated cell proliferation due to genetic or epigenetic mutations

By promoting neurotrophic factor production, chrysin may contribute to neurogenesis and neuronal resilience, potentially reversing depressive symptoms