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They are not from published trials

Standard dosing Daily dose: 300-600mcg per day Injection frequency: Once daily, preferably in the morning on an empty stomach Administration route: Subcutaneous injection Most users start at 300mcg to assess tolerance, then increase to 500-600mcg if the lower dose is well-tolerated but results are modest

One of the reasons many calorie restriction diets are so ineffective in producing weight loss for some is because the human body naturally wants to adjust to the reduced calories by also reducing metabolism

The answer depends on the person, some people benefit from a weekly injection, while others may only need one every two to four weeks

Therefore, patient comfort is paramount