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The effect of nanoparticle size on the ability to cross the bloodbrain barrier: an in vivo study

It is a well-established principle in chemistry called the Arrhenius equation, and it applies directly to peptides in solution

10.1073/pnas.0608449104 168 MagnierC.BoironO.Wendling-MansuyS.ChabrandP.DeplanoV

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Another issue requiring further investigation is whether stabilization of intestinal barrier represents suitable approach to prevent the development of full-blown RA in subjects with evidence of preclinical disease or to treat patients with established synovitis