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Mood Changes : Feeling depressed, anxious, or irritable

Palmitate triggers inflammation through TLR4 not by acting as its direct agonist, but by altering cellular metabolism and membrane composition, thereby licensing TLR4-dependent inflammatory responses [36]

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TLR9 is functionally expressed in microglia and astrocytes, which serve as the brains primary immune effector and supporting glial cells, respectively [129]