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Trace elements, such as iron and zinc, are sequestered by the host organism as part of regulatory nutritional immunity, which is designed to reduce pathogenicity during infection by starving pathogens of trace minerals [73]

Common digestive MTHFR symptoms include: IBS (Irritable Bowel Syndrome) alternating constipation and diarrhea, cramping, or abdominal pain Chronic bloating and gas feeling uncomfortable or distended after meals Food sensitivities and intolerances reactions to gluten, dairy, histamine-rich foods, or FODMAPs Leaky gut syndrome increased intestinal permeability leading to systemic inflammation Nausea or acid reflux particularly after eating certain foods Nutrient malabsorption low B12, folate, or iron despite adequate dietary intake Why this happens: Methylation supports detoxification pathways in the liver and helps break down histamine

Accessed July 6, 2023

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