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PAYMENT METHODS IZIPAY PAYPAL WESTER UNION MONEYGRAM TRANSFER TO OUR BANK ACCOUNT PERU GENERAL CONDITIONS All rates for our Peru Packages are expressed in US dollars (subject to currency exchange rates) and are priced per person The rates for Peruvians only include VAT All our rates are subject to availability and circumstances Children under 2 years and 11 months are considered INF (babies) and are not permitted on this tour Children from 3 to 10 years and 11 months are considered DCC (child) and thus eligible for special rates and obliged to share the room with their parents Children over 11 years old are considered adults Minors must travel with an identity document Rates do not apply to holidays, Easter, long weekends, national holidays, Christmas, or New Year

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5 l of metabolites suspension was loaded and resolved on an Acquity UPLC BEH C18 column (1.7 m, 2.1 100 mm, Waters) using mobile phases of water with 0.1% formic acid (buffer A) and acetonitrile with 0.1% formic acid (buffer B) with a flow rate of 0.3 ml/min and 8 minutes long gradient