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It irreversibly binds to the active site then irreversibly deactivates all B6-dependent enzymes

However, its key roles in regulating core pathways, such as the type I interferon antiviral response and NLRP3 inflammasome activation, strongly suggest that it may serve as a critical molecular node linking viral infection, excessive immune response, and myocardial injury (1820)

(2020) Pathophysiology, prevention, and treatment of beriberi after gastric surgery

Folate and cancer: a tale of Dr

Further, it has been reported in this study that copper mediated oxidation of EGCG possibly leads to the formation of polymerized polyphenols