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Similarly, the liver transcriptome profile of the cows receiving RPM supplement during late gestation and early lactation revealed that the methyl donor SAM and antioxidants ( i.e ., glutathione) are increased by the supply of Met (Osorio et al., 2014a)

doi:10.1016/j.enzmictec.2004.08.003 Wen S, Zhang T, Tan T (2005) Optimization of the amino acid composition in glutathione fermentation

Further, one chaperone upregulated during the UPR is Protein Disulfide Isomerase (PDI), which is an essential redox-sensitive activator of PERK (Kranz et al., 2017)