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Despite recommendations from evidence-based guidelines, polypharmacy is still common in clinical practice of BD, reflecting the gap between research and routine clinical practice (Fornaro et al., The reduced understanding of the underlying pathophysiology and neurobiology of the disorder hampered the development of effective drugs

NAD+ helps promote cellular repair, combat mitochondrial damage and maintain optimal cellular health

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The cellRNP mixture was then immediately added to a 16-well nucleofector strip and electroporated using program DN-100 of 4D-nucleofector X system (Lonza, cat

While complete removal remains challenging, significant improvement is possible with the right approach