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Role of -klotho in cyclophosphamide-induced ovarian injury Those individuals who have been diagnosed with POF have a notable decrease in the expression of -Klotho, which suggests a solid connection between decreased levels of -Klotho and the onset of ovarian aging (Xie et al

doi: 10.1007/978-1-4020-6486-9_8 89 BurrageLCThistlethwaiteLStroupBMet al

Applications in Research As a molecular tool to study short peptidemediated signalling pathways Investigation of intracellular signalling networks involving nitric oxideassociated and growth factor-related pathways In vitro studies examining cytoskeletal organisation and cellmatrix interaction dynamics Preclinical or ex vivo experimental models for mechanistic investigation of oligopeptide signalling Specifications Summary Handling, Reconstitution & Stability Weigh under dry conditions

It mainly comprises three amino acids (glutamine, glycine, and cysteine)