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Nrf2 interferes with the escape from cell death by interaction with other signaling pathways such as suppression of proapoptotic Jun Nterminal kinases (JNKs) (Elsby et al

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This upregulation is an adaptive mechanism that cancer cells use to manage oxidative stress, supporting their survival and proliferation in a hostile environment

This product is supplied solely for laboratory research and provides a convenient alternative to lyophilised peptide preparations

As GSTP1 appears not to be expressed in HepG2 cells (Sison-Young et al., 2015), the low activity of CDNB conjugation in lysates from mock-transected cells is most likely due to other GST isoforms (Scharmach et al., 2009)