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531 For example, levels of MnSOD, thioredoxin1, and Bcl-xL (an anti-apoptotic molecule) are significantly decreased in cardiomyocytes from individuals with advanced heart failure

Glutathione is a naturally occurring protein and a powerful endogenous antioxidant, meaning it is produced within the body

5.3 T cell activation by co-stimulatory signals In addition to cytokine and chemokine-mediated regulation, the innate immune system provides essential co-stimulatory signals for T cell activation