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The GPX4-knockdown metM-Wnt lung cells, relative to scramble controls, produced lower metastatic tumor burden regardless of ferrostatin-1 pretreatment (Fig

Major antioxidant systems contained in the plasma membrane include ubiquinone and vitamin E allowing scavenging of damaging free radicals and inhibition of lipid peroxidation

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indica increased antioxidant enzyme activities and antioxidant concentrations in the plants, which synergistically scavenged excess ROS and thus reduced the oxidative damage to cells by ROS