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Hyperglycemia is frequently observed in critically ill patients and is closely correlated with high rate of mortality and morbidity, and it has been shown to worsen inflammation and oxidative stress in ARDS animal models

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Under physiological conditions, NAD + is converted to NAM in NAD + -consuming reactions catalyzed by sirtuins and PARPs (92)

The benefits of intravenous vitamin C therapy are particularly noteworthy for patients managing chronic illnesses or recovering from intense medical treatments

This might be due to the shift of the end of logarithmic growth phase to the time interval included between the first and second day of incubation