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However, the efficacy of EPR-based nanoparticle tumor targeting exhibits significant interindividual variability

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IL-1 family consists of three main types: agonists (IL-1, IL-1, IL-18, IL-33, IL-36, IL-36 and IL-36), antagonists (IL-1Ra, IL-36Ra and IL-38) and anti-inflammatory cytokine (IL-37) ( Table 1 Classifications and clinical applications of IL family members