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The prescription must be individualized for a specific patient, and the formulation must be prepared by a licensed 503A or 503B compounding pharmacy

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The IGF-1 receptor is referred to as the physiologic receptor because IGF-1 binds to it with significantly higher affinity (approximately 100 times higher) than it does to the insulin receptor

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In comparison with HP alone, HP-CQDs have higher phototoxicity and lower dark toxicity, allowing them to be more effective in targeting cancer cells [118]