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doi: 10.1038/s41593-019-0532-y 294 SantosE

The vast majority of intracellular ROS is continuously generated from mitochondria at the ETC, most of which is reduction of molecular oxygen, resulting in superoxide anion (O 2 )

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It will have a beyond-use date of approximately one month after the patient receives it and should be used within 28 days after the first vial puncture