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The patients signed informed consents which discussed the risks of the procedure, including the unknown risk of a new procedure and the novel nature of the procedure that was not FDA-approved

In SLE, nutritional therapy, which involves limiting the protein and carbohydrate intake as well as using nutritional supplements (such as vitamins, minerals, and polyphenols), is often considered a potential approach to managing inflammatory reactions ( 5.4 Application of immunomodulators Reducing the severity and maintenance of tissue homeostasis is the major goal in the treatment of SLE patients using various biological agents, immunosuppressants, glucocorticoids, etc

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Once the pellet is inserted, the insertion site is covered with a small bandage