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Furthermore, although the present study was conducted in a highly controlled hospital setting with healthy volunteers, involved only a limited number of doses, and included adequate washout periods, repeated MDMA or MDA administration, whether in recreational or clinical contexts, may alter pharmacokinetics, increase conversion to MDA, and carry potential risks of serotonergic neurotoxicity [43] and dependence [44]

10.1002/adhm.202100135 162 SunZ.HouY

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7.) Reaction partner of defined enzyme reactions: Glutathione peroxidase, Glutathione reductase

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